Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1937 2
1939 1
1942 2
1948 1
1951 1
1952 2
1953 5
1954 1
1955 5
1956 3
1957 10
1958 5
1959 4
1960 4
1961 6
1962 6
1963 11
1964 16
1965 23
1966 18
1967 26
1968 29
1969 26
1970 22
1971 43
1972 42
1973 38
1974 49
1975 42
1976 28
1977 16
1978 21
1979 20
1980 17
1981 8
1982 26
1983 21
1984 19
1985 22
1986 16
1987 12
1988 15
1989 23
1990 21
1991 20
1992 9
1993 12
1994 17
1995 6
1996 10
1997 11
1998 10
1999 16
2000 18
2001 13
2002 11
2003 18
2004 18
2005 14
2006 21
2007 41
2008 33
2009 42
2010 84
2011 92
2012 72
2013 102
2014 155
2015 192
2016 168
2017 147
2018 139
2019 111
2020 137
2021 62
2022 30
2023 26
2024 3

Text availability

Article attribute

Article type

Publication date

Search Results

2,334 results

Results by year

Filters applied: . Clear all
Page 1
Bisthioureas of pimelic acid and 4-methylsalicylic acid derivatives as selective inhibitors of tissue-nonspecific alkaline phosphatase (TNAP) and intestinal alkaline phosphatase (IAP): Synthesis and molecular docking studies.
Mumtaz A, Saeed K, Mahmood A, Zaib S, Saeed A, Pelletier J, Sévigny J, Iqbal J. Mumtaz A, et al. Bioorg Chem. 2020 Aug;101:103996. doi: 10.1016/j.bioorg.2020.103996. Epub 2020 Jun 3. Bioorg Chem. 2020. PMID: 32563965
The work presented comprises of synthesis of N-acyl-N'-aryl substituted bisthioureas of pimelic acid (1-7) and 3,5-dimethyl pyrazole (11), 1-aroyl-3-aryl thiourea (12) and 1,3,4-oxadiazole (13) derivatives of 4-methyl salicylic acid. ...Compound 7 and 12 whic …
The work presented comprises of synthesis of N-acyl-N'-aryl substituted bisthioureas of pimelic acid (1-7) and 3,5-dimethyl py …
Pimelic acid, the first precursor of the Bacillus subtilis biotin synthesis pathway, exists as the free acid and is assembled by fatty acid synthesis.
Manandhar M, Cronan JE. Manandhar M, et al. Mol Microbiol. 2017 May;104(4):595-607. doi: 10.1111/mmi.13648. Epub 2017 Mar 3. Mol Microbiol. 2017. PMID: 28196402 Free PMC article.
In addition, supplementation with pimelic acid fully restored biotin production in cerulenin-treated cells. These results indicate that pimelic acid originating from fatty acid synthesis pathway is a bona fide precursor of biotin in B. subtilis. …
In addition, supplementation with pimelic acid fully restored biotin production in cerulenin-treated cells. These results indi …
Formation of a biotin precursor, pimelic acid, in yeasts from C18 fatty acids.
Ohsugi M, Miyauchi K, Tachibana K, Nakao S. Ohsugi M, et al. J Nutr Sci Vitaminol (Tokyo). 1988 Aug;34(4):343-52. doi: 10.3177/jnsv.34.343. J Nutr Sci Vitaminol (Tokyo). 1988. PMID: 3236079
The formation of pimelic acid (a biotin precursor) and biotin-vitamers (a mixture of 7-keto-8-aminopelargonic acid and dethiobiotin) from linolenic, linoleic, and oleic acids was observed in certain yeasts belonging to the genera Cryptococcus, Candida, …
The formation of pimelic acid (a biotin precursor) and biotin-vitamers (a mixture of 7-keto-8-aminopelargonic acid and …
Claisen Condensation Reaction Mediated Pimelate Biosynthesis via the Reverse Adipate-Degradation Pathway and Its Isoenzymes.
Bao Q, Zhi R, Zhou S, Zhao Y, Mao Y, Li G, Deng Y. Bao Q, et al. Chembiochem. 2022 Jun 3;23(11):e202200098. doi: 10.1002/cbic.202200098. Epub 2022 Apr 11. Chembiochem. 2022. PMID: 35352865
Pimelic acid is an important seven-carbon dicarboxylic acid, which is broadly applied in various fields. ...It was also the highest titer of pimelic acid biosynthesized by Claisen condensation reaction, laying the foundation for the production o …
Pimelic acid is an important seven-carbon dicarboxylic acid, which is broadly applied in various fields. ...It was also …
Lipid profiling of the Arabidopsis hypersensitive response reveals specific lipid peroxidation and fragmentation processes: biogenesis of pimelic and azelaic acid.
Zoeller M, Stingl N, Krischke M, Fekete A, Waller F, Berger S, Mueller MJ. Zoeller M, et al. Plant Physiol. 2012 Sep;160(1):365-78. doi: 10.1104/pp.112.202846. Epub 2012 Jul 22. Plant Physiol. 2012. PMID: 22822212 Free PMC article.
We provide strong in vivo evidence for a free radical-catalyzed galactolipid fragmentation mechanism responsible for the formation of the essential biotin precursor pimelic acid as well as of azelaic acid, which was previously postulated to prime the immune r …
We provide strong in vivo evidence for a free radical-catalyzed galactolipid fragmentation mechanism responsible for the formation of the es …
Synthesis of the alpha,omega-dicarboxylic acid precursor of biotin by the canonical fatty acid biosynthetic pathway.
Cronan JE, Lin S. Cronan JE, et al. Curr Opin Chem Biol. 2011 Jun;15(3):407-13. doi: 10.1016/j.cbpa.2011.03.001. Epub 2011 Mar 23. Curr Opin Chem Biol. 2011. PMID: 21435937 Free PMC article. Review.
Biotin synthesis requires the C7 alpha,omega-dicarboxylic acid, pimelic acid. Although pimelic acid was known to be primarily synthesized by a head to tail incorporation of acetate units, the synthetic mechanism was unknown. It has recently been …
Biotin synthesis requires the C7 alpha,omega-dicarboxylic acid, pimelic acid. Although pimelic acid was k …
2,334 results